The analysis of available experimental results of high-volume fly ash concrete mechanical properties showed that extensive amount of research had been done so far. However, a comprehensive analysis of basic high-volume fly ash concrete mechanical properties was not found in the literature. Having that in mind, the database of 440 high-volume fly ash concrete and 151 cement concrete mixtures collected from literature was made. The application of European Code EN 1992-1- 1 prediction models for cement concrete mechanical properties, as well as existing proposals for high-volume fly ash concrete properties, were statistically evaluated on the results from the database. The analysis showed that the prediction models defined in EN 1992-1-1 for compressive strength, tensile strength and for modulus of elasticity can be used for high-volume fly ash concrete, in the given form or with modifications proposed in literature, with similar accuracy and variation of results as for cement concrete. Own model for fly ash efficiency prediction was developed.